Research

Research

UConn School of Medicine is home to many cutting-edge research programs with renowned research teams propelling powerful discoveries and innovations. Since the medical school’s inception, part of its institutional fabric has been its commitment to advancing scientific and medical discovery by growing high-quality research programs. Today, our research enterprise has reached new heights with year-after-year landmark funding exceeding $100 million. Our research expertise knows no boundaries spanning across disciplines, campuses, state and international lines, from basic science to clinical research and trials, to translational research at the patient’s bedside, to population, public, behavioral and social health arenas. Our goal is improving the health and well-being of the people of Connecticut and the globe by translating our discoveries into new patient care advances, health care technologies, and biotech start-up companies.

UConn Science in seconds

Science in Seconds

Got a minute? Take a look at our latest research happening.

Science in Seconds

Fruit fly germ cells are visualized by germline-specific expression of Tubulin-GFP (magenta), and DNA is marked by counterstaining with DAPI (cyan). The yellow dots show expression of Stat92E, which gradually declines as the stem cells transform into sperm (Contributed image).

Lab Notes

Read our research blog for the latest study publications.

Lab Notes

“Chia-Ling Kuo et al. demonstrate the Healthspan Proteomic Score (HPS), derived from chronological age and the expression levels of 86 proteins, is a strong predictor of disease and mortality risk. Lower HPS values are associated with higher risks of disease and mortality. Pictured is a “biological clock” representation hinting that proteins inform the HPS, which can inform our healthspan. Here, the clock’s hand is a 3D rendering of growth/differentiation factor 15 (GDF15), a protein predictor of healthspan. Image credit: Bernard L. Cook III, PhD, who conceptualized, illustrated, and composed the final image, and Illustrate, the software used to render GDF15 (Goodsell DS, Autin L, Olson AJ (2019) Illustrate: Software for Biomolecular Illustration. Structure 27, 1716-1720).”

Scientists Develop New Blood-Based Proteomic Score to Predict Healthspan and Disease Risk

UConn School of Medicine study published in PNAS introduces Healthspan Proteomic Score as a biomarker for healthy aging

Research

Faculty in the School of Medicine are actively involved in a variety of innovative and cutting edge basic science, epidemiological, biobehavioral, and clinical/translational research activities. A major focus of this effort is the translation of our discoveries into advances in patient care and the licensing of new technologies and devices to the private sector.

In the News

In the News

CT State Rep. Murray Riley meeting with students and members of the new Galen V. Henderson, MD Stimulate Equity, Education, and Diversity (SEED) Program. (NEDS Photo Credit)

UConn Medical Students Learning to Strike Out Organ Donation Inequities

New England Donor Services Launches New Medical Student Summer Immersion Program to Advance the Future of Organ Donation and Transplant Equity.

Dr. Robert Fuller in blue scrubs in the emergency department

End of an Emergency Medicine Era

Dr. Robert Fuller leaves a legacy at UConn Health and beyond

Group portrait of five outdoors in front of

UConn Health’s Core Lab Director Shares Expertise in Asia

Dr. Anu Maharjan presents at global lab quality workshop in Nepal

A younger person in hospital scrubs gently holds the hand of an older person

Demystifying the Link Between Major Depression and Alzheimer’s Disease

UConn investigators uncover new risk factors linking depression and dementia

UConn Emergency Entrance

UConn John Dempsey Hospital Nationally Recognized for Excellence in Stroke and Heart Attack Care

UConn John Dempsey Hospital has once again been nationally recognized for delivering high-quality, lifesaving care—earning three major 2025 awards from the American Heart Association.

Team that provided the first infusion.

World-First Gene Editing Trial for Rare Genetic Disease at UConn Health

UConn Health and Connecticut Children’s have made history by dosing the first patient in a clinical trial using gene editing to treat glycogen storage disease type 1a (GSD1a)

Dr. Cato T. Laurencin

Professor Sir Cato T. Laurencin of UConn Honored by the American Institute for Medical and Biological Engineering

Sir Cato T. Laurencin, M.D., Ph.D., K.C.S.L, was the designated honored guest at the American Institute for Medical and Biological Engineering (AIMBE) President’s Circle Reception in Washington, DC.

group portrait of four women, two men, indoors

UConn Health Resident Honored for Local, Global Service

Dr. Priscilla Mapelli earns community service award from residency program consortium

Patient being examined by a doctor in a white coat

Multiple Sclerosis Patient Sees Bright Future

From unheard to understood

Explorer AUV (autonomous underwater vehicle) at Australian Maritime College

UConn AUKUS Scholars Explore Undersea Vehicle Technology, International Collaborations in Australia

Five College of Engineering students studied systems thinking and interdisciplinary teamwork essential in modern undersea vehicle development

Cows grazing in their pastures

Finding New Strategies for Treating a Catastrophic Disease

Foot and Mouth Disease was eradicated in the US in 1929, and researchers are working to make sure it stays that way

California's Salton Sea lake, with dead trees and a blue sky.

Geothermal Brine May Hold a Key to Stored Energy Challenges

Making domestic lithium recovery economically and environmentally viable is a critical goal for meeting the nation’s increasing appetite for energy storage and sustainability

Got Research News?

Do you have an embargoed research publication or national meeting abstract presentation coming up? If you think it might catch the media’s attention due to its significant impact on the future of health sciences or patient care, please fill out this online form before the embargo lifts to have it featured by UConn Health’s News Team.