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  • UConn Health Center Learning Equipment
    Advancing knowledge through basic, biomedical, clinical, translational, behavioral, and social research.
  • Patient Tower 2015
    Providing educational opportunities for those pursuing careers in the patient care professions, education, public health, biomedical and/or behavioral sciences.
  • two female uconn health doctors
    Helping health care professionals maintain their competence through continuing education programs.
  • UConn Health First in New England to Offer Robot-Guided Spine Surgery
    Developing, demonstrating, and delivering health care services based on effectiveness, efficiency, and the application of the latest advances in clinical, translational and health care research.
  • The School's new circular teaching hall.
    New teaching center for team-based learning.

The mission of the UConn School of Medicine is innovation, discovery and education. We train the next generation of medical students, residents, specialty fellows, and clinical practitioners in an environment of exemplary patient care, research, and public service.

Information For:

user icon Prospective Students stethoscope icon Current Students Hospital icon Residents and Fellows medical pprofessional icon Faculty cap icon Alumni and Friends
  • two female uconn health doctors
    Helping health care professionals maintain their competence through continuing education programs.
  • UConn Health Center Learning Equipment
    Advancing knowledge through basic, biomedical, clinical, translational, behavioral, and social research.
  • UConn Health First in New England to Offer Robot-Guided Spine Surgery
    Developing, demonstrating, and delivering health care services based on effectiveness, efficiency, and the application of the latest advances in clinical, translational and health care research.
  • The School's new circular teaching hall.
    New teaching center for team-based learning.
  • Patient Tower 2015
    Providing educational opportunities for those pursuing careers in the patient care professions, education, public health, biomedical and/or behavioral sciences.

The mission of the UConn School of Medicine is innovation, discovery and education. We train the next generation of medical students, residents, specialty fellows, and clinical practitioners in an environment of exemplary patient care, research, and public service.

Information For:

user icon Prospective Students stethoscope icon Current Students Hospital icon Residents and Fellows medical pprofessional icon Faculty cap icon Alumni and Friends

News

The clinical trial originally set out to simply test the safety and dosage of the gene therapy for three patients with GSD Type Ia. The dramatic improvement in their lives was unexpected.
World’s First Gene Therapy for Glycogen Storage Disease Produces Remarkable Results

The clinical trial originally set out to simply test the safety and dosage of the gene therapy for three patients with GSD Type Ia. The dramatic improvement in their lives was unexpected.

Read More

UConn Health Academic Building
School of Medicine Receives Full Accreditation

The Liaison Committee on Medical Education (LCME) made the decision to grant UConn School of Medicine full accreditation of its medical education program for an eight-year term, the maximum term allowable. The LCME is recognized by the U.S. Department of Education as the reliable authority for the accreditation of medical education programs.

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UConn School of Medicine's Lakshmi Nair, Ph.D., accepting her 2019 GWIMS award presented by Liisa Kuhn, Ph.D.
Outstanding Women in Medicine and Science Honored

The Group on Women in Medicine and Science (GWIMS) at UConn Health held its annual symposium May 6 to honor outstanding women faculty, and other standout female graduate, medical and dental students.

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News

The clinical trial originally set out to simply test the safety and dosage of the gene therapy for three patients with GSD Type Ia. The dramatic improvement in their lives was unexpected.
World’s First Gene Therapy for Glycogen Storage Disease Produces Remarkable Results

The clinical trial originally set out to simply test the safety and dosage of the gene therapy for three patients with GSD Type Ia. The dramatic improvement in their lives was unexpected.

Read More

UConn Health Academic Building
School of Medicine Receives Full Accreditation

The Liaison Committee on Medical Education (LCME) made the decision to grant UConn School of Medicine full accreditation of its medical education program for an eight-year term, the maximum term allowable. The LCME is recognized by the U.S. Department of Education as the reliable authority for the accreditation of medical education programs.

Read More

UConn School of Medicine's Lakshmi Nair, Ph.D., accepting her 2019 GWIMS award presented by Liisa Kuhn, Ph.D.
Outstanding Women in Medicine and Science Honored

The Group on Women in Medicine and Science (GWIMS) at UConn Health held its annual symposium May 6 to honor outstanding women faculty, and other standout female graduate, medical and dental students.

Read More

Spotlight

Golda Ginsburg, Ph.D., sitting in the patient waiting room smiling at the camera

Golda S. Ginsburg, Ph.D.

Meet Professor of Psychiatry, Department of Psychiatry, Golda S. Ginsburg, Ph.D.

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Events

  1. Oct 16 Neuroscience Journal Club - Ramasamy12:00pm

    Neuroscience Journal Club - Ramasamy

    Wednesday, October 16th, 2019

    12:00 PM - 01:00 PM

    UConn Health
    E4036

    MEDS 6497 - Neuroscience Journal Club

    Paper to be presented:
    "Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination"

    Presenter: Ramalakshmi Ramasamy, Graduate Assistant, Smith Lab

    Citation link: https://www.nature.com/articles/s41467-019-11638-3

    Contact Information: Jody Gridley, gridley@uchc.edu, 860-679-8787

    More
  2. Oct 17 Neuroscience Seminar Series - Verma11:00am

    Neuroscience Seminar Series - Verma

    Thursday, October 17th, 2019

    11:00 AM - 12:00 PM

    UConn Health
    Low Learning Center

    Sponsored by the Kim Family Fund

    "Role of immune infiltration and purinergic receptor P2X4 in ischemic stroke"

    Presenter:
    Rajkumar Verma, Ph.D.
    Assistant Professor, Department of Neuroscience, UConn Health, Farmington, CT

    Relevant citation link: "https://www.ncbi.nlm.nih.gov/pubmed/28751018/"

    Contact Information: Jody Gridley, gridley@uchc.edu, 860-679-8787

    More
  3. Oct 17 CCAM Seminar Series - Froehlich12:00pm

    CCAM Seminar Series - Froehlich

    Thursday, October 17th, 2019

    12:00 PM - 01:00 PM

    UConn Health
    CGSB, CCAM Conference Room, R1673, 400 Farmington Ave

    CCAM Seminar Series
    Speaker: Fabian Froehlich Ph.D., Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School
    Title: "Thermodynamic Modeling of ERK and EGFR signaling reconciles apparent drug interactions with molecular mechanisms"
    Host: Dr. Michael Blinov
    Abstract:Allosteric interactions are at the core of many signal transduction processes and provide robustness and enable context dependency for the underlying molecular mechanisms. In the context of RAF inhibitors allosteric interactions give rise to paradoxical activation, a clinically observed phenomenon where RAF inhibitors effectively decrease tumor growth in BRAF mutant cancers but promote tumor growth in BRAF wild-type cancers. Energy based formalisms to describe such allosteric effects in kinetic models have been developed, but are so far rarely applied in practice, which is likely to be a result from the high complexity of the generated models.

    Here we demonstrate the use of a thermodynamic, energy-balanced rule-based formalism to describe allosteric interactions. We tackle the numerical challenges of large kinetic models by using state of the art simulation tools and address the conceptual challenge of analyzing large kinetic models by exploiting the strong structure imposed on the model by the rule-based formalism and energy balance.

    We apply these methods to an ordinary differential equation model of adaptive resistance in melanoma (EGFR and ERK pathways, >1k state variables, >10k reactions). We trained the model on absolute proteomic and phospho-proteomic as well as time-resolved immunofluorescence data, both in dose-response to small molecule inhibitors. We identify and explain a time-scale separation between transcriptional feedbacks and phospho-signaling. Moreover, we illustrate how kinetic models can extrapolate from single drug treatments to drug combinations.

    Contact Information: Tiffany Jespersen

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  4. Oct 22 MBB Seminar: Dr. Karin Crowhurst12:00pm

    MBB Seminar: Dr. Karin Crowhurst

    Tuesday, October 22nd, 2019

    12:00 PM - 01:00 PM

    UConn Health
    Low Learning Center

    Investigating the mechanism of activation and function of acid stress chaperones

    Contact Information: Bridget Clancy-Tenan, 860-679-2108, clancy@uchc.edu

    More
  5. Nov 5 MBB Seminar: Dr. Stavroula Hatzios12:00pm

    MBB Seminar: Dr. Stavroula Hatzios

    Tuesday, November 5th, 2019

    12:00 PM - 01:00 PM

    UConn Health
    Low Learning Center

    Biochemical crosstalk at the host-microbe interface

    Contact Information: Bridget Clancy-Tenan, 860-679-2108, clancy@uchc.edu

    More
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